In a California courtroom, seventeen-year-old Nou Lee reels with what she is about to do. What she must do to survive. She reflects on the splintered path that led to this moment, beginning twelve years ago in 1978, when her Hmong family escaped from Laos after the Communist takeover. The story follows the Lees from a squalid refugee camp in Thailand to a new life in Minnesota and eventually California. Family members struggle to survive in a strange foreign land, haunted by the scars of war and loss of family. Across the Mekong River paints a vivid picture of the Hmong immigrant experience, exploring family love, sacrifice, and the resiliency of the human spirit to overcome tragic circumstances.